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doi: 10.1016/j.pbiomolbio.2015.05.001

In conjunction with these strategies, clinicians often advise lifestyle modifications, such as dietary changes and exercise, to further mitigate side effects and optimize weight loss outcomes

(2020) 105:e2695e709

The STEP Program: Weight Loss in People Without Diabetes The STEP 1 trial (N=1,961) enrolled adults with a BMI of 30 or greater (or 27 or greater with a comorbidity) and excluded anyone with diabetes